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KMID : 0362720130510030138
Journal of the Korean Dental Association
2013 Volume.51 No. 3 p.138 ~ p.147
Biomechanical adaptation of orthodontic tooth movement
Lee Syng-Ill

Abstract
Orthodontic tooth movement is a unique process which tooth, solid material is moving into hard tissue, bone. Orthodontic force in general provides the strain to the PDL and alveolar bone, which in turn generates the interstitial fluid flow(in detail, fluid flow in PDL and canaliculi). As a results of matrix strain, periodontal ligament cells and bone cells are deformed, releasing variety of cytokines, chemokines, and growth factors. These molecules lead to the orthodontic tooth movement(OTM). In these inflammation and tissue remodeling sites, all of the cells could closely communicate with one another, flowing the information for tissue remodeling.
To accelerate the rate of OTM in future, local injection of single growth factor(GF) or a combination of multiple GF¡¯s in the periodontal tissues might intervene to stimulate the rate of OTM. Corticotomy is effective and safe to accelerate OTM.
KEYWORD
orthodontic force, fluid flow, strain, cytokine, chemokine, growth factor, orthodontic tooth movement (OTM)
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